Abstract

A CASE REPORT OF ORAL MUCOSAL CANDIDIASIS INDUCED BY STEROID THERAPY IN IMMUNOCOMPROMISED PATIENT

Dr. S. Lakshmi Sabapathi*, K. Syedraja, R. Gunaseelan and C. Mayakrishnan

ABSTRACT

Oral mucosal candidiasis is the most common fungal infection of the oral cavity, which frequently affects extremely young, elderly, and ill people. It is one of the adverse effects associated with the usage of corticosteroids. It happens in persons taking glucocorticoids or antibiotics, immunosuppressed people, and people who have HIV infection. We report here a case of oral mucosal candidiasis induced by corticosteroid therapy. A 58-year-old male patient reported the chief complaint of fever and shortness of breath, multiple rashes all over the body with skin peeling for 1-week, gradual onset, progressive in nature. The patient had a history of Neurosurgery done for EDH and started Phenytoin. So, the patient had phenytoin-induced Steven-Johnson syndrome. He was treated with corticosteroids and anti- microbials in the hospital. On fifth-day intra-oral examination showed signs of discharge, a white moss-like appearance, ulcerative lesions of the lips, base of the tongue, buccal mucosa along with bad breath and fissures at the angles of the mouth. Based on both clinical examination and investigations; the diagnosis indicates Oral mucosal Candidiasis due to the usage of corticosteroids. Initially, all the steroid drugs are tapered off and he was treated with anti-fungal also he responded to Antifungal therapy and recovered completely without the necessity of further therapy. Therefore, all clinicians need to detect candida infections during routine exams and administer the proper care. Eliminating any identified risk factors and administering the proper antifungal medications are required to effectively diagnose oral candidiasis.

Keywords: Corticosteroids, Oral mucosal candidiasis, Ulcerative lesions in lips, Antifungals.