Abstract

ANTHELMINTIC ACTIVITY OF CRUDE EXTRACT OF GREWIA TENAX

*Syeda Jeelani Basri T, Dr. G.V.Subba Reddy, Dr. K.N.Jayaveera

ABSTRACT

The present study aimed at the in-vitro evaluation of anthelmintic activity of ethanolic extracts of whole plant of Grewia Tenax using Pheretima posthuma at four different concentrations(25, 50, 100, and 200 mg/ml) respectively. The study involved the determination of time of paralysis (P) and time of death (D) of the worms. At the concentration of 100 mg/ml both the ethanolic and the aqueous extracts exhibited very significant activities as compared to the standard drug. Albendazole (10 mg/ml). The time of paralysis and death was Recorded in case of n-haxane extract, Ethanolic extract and Hydro-alcoholic extract. In conclusion, the use of whole plant of Grewia Tenax an anthelmintic have been confirmed and further studies are suggested to isolate the active principles responsible for the activity.

Keywords: Grewia Tenax, Anthelmintic, Pheretima posthuma, Albendazole