Abstract

NEPHROPROTECTIVE ACTIVITY OF PUNARNAVA COMPOUND IN CKD- A PHARMACEUTICAL STUDY

Dr. S. V. Bagade*

ABSTRACT

Chronic renal failure (CRF) refers to an irreversible deterioration in renal function, which develops over a period of years. This initially manifests only as a biochemical abnormality. CRF is considered when glomerular filtration rate (GFR) falls below 30 ml/min. The conventional approach of management includes dialysis and renal transplantation, which are not affordable by Indian population mainly due to economic reasons. Therefore, exploration of a safe and alternative therapy is needed, which proves to be helpful in reducing the requirement of dialysis and in postponing the renal transplantation. Punarnava drug is a diuretic, which means that it stimulates regular and plenty of urination. This helps keep the body clean. Furthermore, regular urination also clears out the calcium accumulated in the kidneys, thus preventing kidney stones from occurring. The diuretic properties of Punarnava root powder also help prevent dropsy, a condition in which water or watery fluids settle down in the tissue and cavities of the body and cause problems with the health.

Keywords: Punarnavadi compound, CKD, Pharmaceutical study.