Abstract

INVESTIGATION OF IN-VITRO ANTIOXIDANT AND CYTOTOXICITY OF GREEN SYNTHESIZED SILVER NANOPARTICLE USING PEPEROMIA PELLUCIDA (L.)

Shilpa V. P.*, Sirrajudheen M. K., Jilsha G., Sruthy P.N., Sangeetha Vijayan U., Mukesh M., Sruthi T.P.

ABSTRACT

Plant-mediated biosynthesis of silver nanoparticles (AgNPs) and the microbiological activity on selected pathogenic microorganisms is discussed. In this study, aqueous extracts of the aerial parts of a medicinal herb, Peperomia pellucida, were utilized to construct AgNPs. The synthesized AgNPs were characterized by ultraviolet–visible, Fourier-transform infrared (FT-IR), and X-ray diffraction spectrometer and scanning electron microscopy analysis. A characteristic peak of 570 nm showed the absorption spectrum of silver nanoparticles. The crystalline structure of the synthesized nanoparticles is confirmed by XRD analysis and it having the diffraction values at 35.45°, 44.32°, and 65.25° degrees. FE-SEM analysis conforms to the nanoparticle size and shape. The silver nanoparticles investigated antioxidant and cytotoxicity. From the antioxidant and cytotoxicity results concluded that it having significance antioxidant (DPPH) and cytotoxicity activity (SK-MEL- 3 cell lines).

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