Abstract

TRANSDERMAL DRUG DELIVERY PATCHES: A NOVEL DRUG DELIVERY APPROACH: A REVIEW

Asst Prof. Sagar Suresh Jadkar*, Krishna Rajesh Chhoda, Insha Nashir Deshmukh, Shravani Ashok Gawali, Renuka Sanjiv Adsul, Ashwini Vijay Tikate, Bhavana Balasaheb Pawar, Aditya Pradip Patil

ABSTRACT

Human skin is a readily accessible surface for drugs delivery. The skin of the average adult body is You receive about a third of about 2m2. Blood that circulates throughout the body. Over the past few decades, Development of controlled drug delivery increasingly important in the pharmaceutical industry. of The average human skin surface is 10- 70 hair follicles and 200-250 sweat glands in each square Centimeters of skin surface. it is one of the easiest accessible organs of the human body. there are quite a few Interest in the skin as a drug application site for both Local and systemic effects. But especially the skin The stratum corneum represents a formidable barrier to drugs Penetration, thereby limiting topical and transdermal bioavailability. A transdermal patch is a medicated patch placed on the skin to deliver a specific dose of medicine through the skin and into the bloodstream. Often this promotes healing of injured areas body. Advantages of the transdermal route of drug delivery over other types Administration of drugs, such as oral, topical, intravenous, intramuscular. is to ensure the controlled release of the drug to the skin by the patch to Patients usually. A thin layer of embedded drug or drug that melts at body temperature with glue. The primary goal of transdermal drug delivery systems is to deliver drugs through the skin into the systemic circulation at a predetermined rate with minimal inter- and intra-patient variability.

Keywords: Transdermal, Patch, Skin, bioavailability, Penetration.