Abstract

STUDY ON ESLICARBAZEPINE ACETATE IN ADULT GENERALIZED SEIZURES

BhargavDilipSeeram*, SundarShanmugam, Kishore Kinnera, JayasuthaJayram, Muthuraj Krishnan

ABSTRACT

The treatments for seizures are usually aimed at improving the clinical condition of the patient by reducing the seizure frequency and adverse drug reactions.Eslicarbazepine acetate is a newly approved antiepileptic drug used as adjunctive therapy for partial onset seizures. Objective: The objective of this study is to evaluate the efficacy of Eslicarbazepine acetate and also to assess adverse drug reactions of Eslicarbazepine acetate. Method: This study was a prospective interventional study. A total of 35 patients were included in the study. Results: After administration of Eslicarbazepine acetate, all patients (100%) were seizure free with very low incidence of adverse effects. Majority of patients experienced sleepiness, headache, confusion, fatigue, agitation and memory problems. Conclusion:Eslicarbazepine acetate monotherapy was found to be effective and safe in partial and generalized seizure patients.

Keywords: Seizures, Eslicarbazepine acetate, Adverse drug reactions, Seizure frequency