Abstract

A BRIEF REVIEW ON THE POROUS ORGANIC CAGES

Yu Zhou, Bo Yuan, Wen-Dong Xu, Ren-Wang Jiang*

ABSTRACT

Purpose: The objective of this study was to describe the major categories and preparation methods of porous organic cages and the applications in chemical and biomedical sciences. Methods: The databases including Pubmed, Scifinder, Google Scholar and Cambridge Structure Database were searched, and the related literatures were analyzed. Results: Porous organic cages (POCs) were a class of organic molecules with permanent cavity connected by covalent bonds. Some POCs had intrinsic cavities, while others just had extrinsic cavities. Different methods including the Schiff-base condensation, olefin/alkyne metathesis, formation of hydrazone, boronic acid condensation and some other none dynamic covalent coupling reactions could be used for the synthesis of POCs. The POCs showed functions in gas storage, guest isolation, sugar recognition, polution removement, enhanced radiosensitivity and biological imaging. Conclusion: POCs were excellent molecules in term of the intriguing chemistry and rich functions.

Keywords: Porous organic cages, synthesis, functions.