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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

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New Impact Factor

WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS: MAY ISSUE PUBLISHED

May Issue has been successfully launched on 1 May 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

Scope Indexed

WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

Abstract

NANOSUSPENSION: AN OVERVIEW

Diksha M. Kachare*, Shaikh Salva Midhat, S. B. Bothara

ABSTRACT

The most common issue related with poorly water-soluble drug is very low bioavailability. These problems mostly associated with Biopharmaceutical classification system (BCS) class 2 of drug (e.g. Simavastatin, itraconazole, Carbamazepine etc.). Formulation as nanosuspension is a desirable and promising strategy to overcome these challenges. Nanosuspension is a colloidal dispersion of nanosized drug particles and stabilized with surfactants. The substance is suspended in dispersion as a pure, inadequately water-soluble nanosuspension. A nanosuspension not only addresses the issues of low solubility and bioavailability but also changes the pharmacokinetics of the drug, enhancing both efficacy and safety. This review article describes a method of preparation, evaluation, applications of the nanosuspension.

Keywords: Nanosuspension, solubility, bioavailability, pharmacokinetic, colloidal dispersion.

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