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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

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Abstract

RHIZOME DRYNARIA QUERCIFOLIA AND ITS ANTI-INFLAMMATORY ACTIVITY – REVIEW

Lavanya N.*, Sowmiya Devi B., Kalaimani S. and Dr. J. Bagyalakshmi

ABSTRACT

The rhizomes Drynaria quercifolia was mainly used in treating ailments like bone fracture, cholera, headache, jaundice, rheumatism and vomiting. The present study was aimed to justify the medicinal use of rhizome Drynaria quercifolia as anti-inflammatory agent. The rhizome is powdered and extracted using methanol and water. The invitro studies are studied using inhibition of albumin denaturation, membrane stabilization test and cox1 & cox2 inhibition assay. The in-vivo studies studied using carrageenan induced paw edema. Both the extracts show significant inhibition of protein denaturation and carrageenan induced method and MEDQ is more significant. These results claims that the rhizome Drynaria quercifolia possess anti- inflammatory activity mainly due to cox1 and cox2 inhibition.

Keywords: Drynaria quercifolia, Anti-inflammatory, cyclooxygenase and paw edema.

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