Abstract

MANAGEMENT OF ISCHEMIC STROKE: A REVIEW

Akansha Chauhan*, Garima Gupta and Anil Kumar

ABSTRACT

Ischemic stroke exacts a heavy toll on death and disability worldwide. In the United States, where it is the third leading cause of death and the leading cause of serious long-term disability, approximately 750,000 strokes occur annually, with an annual mortality rate exceeding 150,000. Ischemic stroke is the most common type of stroke and occurs when a blood vessel in the brain is blocked. The blockage can be caused by "the formation of a clot within a blood vessel of the brain or neck, called thrombosis; the movement of a clot from another part of the body such as the heart to the brain called embolism; or a severe narrowing of an artery in or leading to the brain, called stenosis. The treated within 6 hours of stroke symptom onset, mechanical thrombectomy with a second-generation stent retriever or a catheter aspiration device should be indicated regardless of whether the patient received treatment with intravenous (IV) recombinant tissue plasminogen activator (rtPA) in patients with limited signs of early ischemic changes on neuroimaging. But it contains the risk of surgery in older persons and treatment should be within a limited time. So it is required better pharmacological treatment for recovery in which a combination of various therapies should be applied i.e. antioxidant, antiplatelet, hypolipidaemic, antihypertensive, and clot disruption therapies. Conclusion: So it is required better pharmacological treatment for recovery in which a combination of various therapy should be applied i.e. antioxidant, antiplatelet, hypolipidaemic, antihypertensive, and clot disruption therapies.

Keywords: Ischemia, stroke, tPA, antioxidant, antiplatelets.