Abstract

A GENERAL REVIEW ON NOVEL DRUG DELIVERY SYSTEM

Aishwarya Sanjay Shinde* and Rahul Raosaheb Sinare

ABSTRACT

Improved therapy by increasing the efficacy and duration of drug activity, increased patient compliance through decreased dosing frequency and convenient routes of administration, and improved targeting for a specific site to reduce unwanted side effects are just a few of the many advantages of novel drug delivery systems (NDDS). Delivering both established and emerging drug technologies in a manner that enhances patients' benefits presents a challenge for both drug manufacturers and drug delivery companies. Bioactive and plant extracts have been used to create a variety of novel formulations, including polymeric nanoparticles, nanocapsules, liposomes, phytosomes, nanoemulsions, microspheres, and hydrogels, in the development of novel drug delivery systems (NDDS) over the past few years. Enhancement of solubility, bioavailability, protection from toxicity, enhancement of pharmacological activity, enhancement of stability, improved tissue macrophage distribution, sustained delivery, and protection from physical and chemical degradation are reported to be significant advantages of the novel formulations over conventional anticancer formulations. The method of preparation, type of active ingredients, size, entrapment efficiency, route of administration, biological activity, and applications of novel formulations are all summarized in this review, which highlights the current state of development.

Keywords: Drug Delivery System, New Drug Delivery System, NDDS.