Abstract

PHARMACOGNOSTICAL AND PHARMACEUTICAL ANALYSIS OF BHRINGARAJA RASAYANA TABLET-AN AYURVEDIC HERBAL FORMULATION FOR PRAMEHA-PURVAROOPA (PRE-DIABETES)

Dr. Karan Surati*, Dr. Mandip Goyal, Dr. Harisha C.R. and Dr. Vinay Shukla

ABSTRACT

Background: Bhringaraja Rasayana tablet is an Anubhuta yoga which is given as one of the drugs for management of metabolic syndrome and as a hepato-protective drug. So for initialization of standardization and assurance of quality of herbal preparation pharmacognostical and pharmaceutical analysis should be done. Methods: Bhringaraja Rasayana tablet was subjected to microscopic evaluation for pharmacognostical, physiochemical analysis like loss on drying, ash value, pH value, acid insoluble ash, water soluble extract, alcohol soluble extract and high-performance thin layer chromatography (HPTLC). Results: Pharmacognostical study showed the presence of certain identifying characters of the main ingredient of Bhringaraja Rasayana tablet which is Bhringaraja only. In pharmaceutical study, preliminary physiochemical analysis showed that ash value is 10.27% w/w, loss on drying 4.1% w/w, water soluble extract 20.90% w/w, alcohol soluble extract 7.6% w/w and HPTLC showed 3 spots in 254 nm and 6 spots in 366 nm. Conclusions: Pharmacognostical and physico-chemical observations revealed the specific characters of active constituents of Bhringaraja Rasayana tablet and confirmed the purity and genuinity of the drug.

Keywords: Bhringaraja Rasayana tablet, Prameha-Purvaroopa, pre-diabetes, pharmacognosy, pharmaceutical analysis.