Abstract

A RETROSPECTIVE OBSERVATIONAL STUDY ON DEFINED DAILY DOSE AMONG PATIENTS WITH CHRONIC KIDNEY DISEASE

Devika S., Jyothy A., Sharon Emilia James, Dr. Akhila S. Arjun, Dr. Anitha Mary Mathews*

ABSTRACT

Drug Utilization Review (DUR) is defined by the WHO as the marketing, distribution, prescription and use of drugs in a society, with special emphasis on the resulting medical, social and economic consequences. In our study out of 100 patients there were more male patients (67%) as compared to the female patient (33%) and majority of the patients were in the age group of 61-80 years (49%). This study reveals that hypertension is the most diagnosed comorbidities in both male and female patients, followed by diabetes mellitus. There are 13 irrational antibiotics that were prescribed in the study population, out of which the highest was seen in Tab. CEFIXIME (OID-6) followed by Inj. MEROPENEM. The most commonly prescribed 6 antibiotics were classified in the study using the ATC classification system and drug utilization was measured as DDD per 1000 inhabitants per day. Ceftriaxone+ Sulbactam (J01DD04) was the most commonly prescribed antibiotic with DDD per 1000 inhabitants per day (0.7206) followed by Cefixime (J01DD08) with DDD per 1000 inhabitants per day value 0f 0.6005. The above result shows that an active intervention by the clinical pharmacist in process of DDD will improve the rational use of drug in patients.

Keywords: Drug Utilization Review (DUR), World Health Organisation(WHO), Defined Daily Dose (DDD), Prescribed Daily Dose (PDD).