Abstract

FORCE DEGRADATION STUDY TO STABILITY INDICATING METHOD

Shubhangi Shete*, Chaitali Dhale, Suhas Joshi, Ratnakar Hole.

ABSTRACT

The stability of drug product or a drug substance is a critical parameter which may affect purity, potency and safety. The stability indicating method is that employed for the analysis of stability samples in pharmaceutical industry. Forced degradation studies show the chemical behavior of the molecule which in turn helps in the development of formulation and package. Forced degradation is a degradation of new drug substance and drug product at conditions more severe than accelerated condition. Thus, this review discuss the current trends in performance of stability indicating method to force degradation by providing strategy for conducting studies on degradation mechanism

Keywords: Stability indicating method, forced degradation study.