Abstract

CLINICAL MANIFESTATION OF PREVENTIVE MEASURES AND MANAGEMENT OF SARS-COV-2 INFECTION IN PREGNANT WOMEN: AN UPDATE

Himanshu Ranjan*, Kumari Reshu, Dr. Krishna Murti and Dr. Nitesh Kumar

ABSTRACT

Changes in physiology, mechanics, and immunology during pregnancy may impact COVID-19 risk and severity of symptoms. Expected mothers are more susceptible to SARS-CoV-2 infection than non-pregnant women due to a lack of comparative incidence statistics and difficulty differentiating susceptibility from other exposure hazards. Pregnant women were more likely than non-pregnant women of reproductive age to be hospitalized to critical care, require invasive ventilation and extracorporeal membrane oxygenation, and die. SARS-CoV-2 has been found to be transferred intra-arterially, however, this is rare. Pregnant women are at risk for severe SARS-CoV-2 infections due to previous corona virus illnesses like SARS and MERS. Pregnancy significantly changes the immunological, respiratory, cardiovascular, and coagulation systems. These variables may help or hinder COVID-19 illness progression. In utero effects of this virus on implantation, foetal growth and development, labour, birth, and infant health are unknown. Asymptomatic infections provide unique problems in terms of service delivery, prevention, and management. This may explain the low levels of SARS-CoV-2 viremia in the placenta. SARS-CoV-2 infection is linked to an increase in preeclampsia, premature birth, and stillbirth in pregnant women with severe COVID-19 disease. The pandemic's effects on healthcare systems have led to an increase in stillbirths and maternal mortality. Health disparities between mothers and newborns appear to be growing, reversing previous advances. Pregnant or lactating women can receive any of the three COVID-19 vaccines now available in the US. With so many women being vaccinated so early in pregnancy, additional information

Keywords: concerning the outcomes of birth is needed, especially among those who were vaccinated earlier in pregnancy.