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Abstract

PHYTOCHEMICAL ANALYSIS AND ANTI-INFLAMMATORY ACTIVITY OF NYCTANTHES ARBOR TRISTIS LINN: A CRITICAL REVIEW

Indu Mittal*, Dr. K. Sarvanan and Dr. Amarjeet Singh

ABSTRACT

Theanti-inflammatory effect and phytochemical analysis of Nyctanthes Arbor Tristis Linnis been critically reviewed in this article based on the available literature and refrences. The plant is its self a treasure of the various classes of the phytochemicals and which are responsible for the various pharmacological activities. Majorly, β-Sitosterol, hentriacontane, benzoic acid, astragalinare present in the leaves which influence the activities of the pro-inflammatory mediators and cell signaling pathways in the nucleus and cytoplasm. In response, Interleukin-6, Interleukin-1, and Tumor Necrosis Factor restricted and activate the Janus kinase signal transducer (JNK) and p38 pathways in the nucleus and again restricted the activity of the inflammatory mediators in the cytoplasm.

Keywords: Nyctanthes Arbor Tristis, Anti-inflammatory, Janus kinase signal transducer (JNK) path ways.


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