Abstract

FORMULATION AND EVALUATION OF GEL

Shilpa Shyam M.* and Kadeejath Shabna

ABSTRACT

Topical drug delivery has advantages such as applying the drug directly into skin and it also provides prolonged action on the specific site. There are different topical used formulation among the semisolid dosage forms gel formulations are becoming pre-eminent. Gels are colloids that are 99% liquid by mass, which is immobilized by surface tension among it and a macromolecules system of fibres constructed from a less amount of gelatinous substances present. The nature of solvent used categorizes gel into mainly two basic types ie, hydrogel and organogel. This article includes fundamental advantages of gel formulation above other semisolid formulation and also other aspects like limitation, classification, formulation, mechanism involved and factors affecting gel formulation.

Keywords: Skin, Pharmaceutical gels, Characteristics, Carbopol, Evaluation, keratinocyte.