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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS: MAY ISSUE PUBLISHED

May Issue has been successfully launched on 1 May 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

Scope Indexed

WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

Abstract

ANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF RP-HPLC AND SIMULTANEOUS ESTIMATION OF MOXONIDINE IN PHARMACEUTICAL DOSAGE FORM

Shivani S. Yendhe*, Shubham S. Pate, Hemant V. Kamble, Ashwini K. Andhale and Santosh A. Waghmare

ABSTRACT

A simple, sensitive, and selective isocratic reversed phase High Performance Liquid chromatographic method has been developed for estimation of moxonidine from pharmaceutical dosage form using a mobile phase consisting mixture Methanol: Water (80:20), at the flow rate of 0.8mL/min . A cosmosil C18 A (250mm X 4.6 mm, 5micron particle diameter) column was used as a stationary phase. The retention time of moxinidine 2.09 min. the eluent were detected at 252nm. The proposed method is precise, accurate, selective and rapid for the determination of Moxonidine.

Keywords: Moxonidine, RP-HPLC Method, Mobile phase.

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