Abstract

PREPARATION AND EVALUATION OF MICROSPHERES AND ITS UPDATED APPLICATION: AN OVERVIEW

Buddhi Prakash Kashyap*, Neeraj Pandey and Maneesha Rana

ABSTRACT

Multi-particulate drug delivery systems called microspheres are created to accomplish delayed or regulated medication administration in order to boost bioavailability and stability. Synthetic polymers like vinylic polymer and polydopamine were employed in a straightforward production process to make microspheres. Additionally, biodegradable and environmentally benign natural polymers (such cellulose, alginate, and chitosan) are employed. The current review focuses on distinct kinds of microspheres, a range of preparation techniques, potential uses, and numerous efficiency-testing metrics. A variety of delivery methods, including oral, parenteral, nasal, ocular, transdermal, colonal, and ophthalmic, are available for microspheres with particle sizes ranging from 0.1 to 200 micrometer. Microspheres will play a key role in novel drug delivery in the future by fusing together numerous new tactics, particularly in the sorting of damaged cells, genetic materials, safe, targeted, and efficient drug delivery.

Keywords: Microspheres, Novel drug delivery, Bioavailability, Natural polymer, Vinylic polymer.