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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

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New Impact Factor

WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS: MAY ISSUE PUBLISHED

May Issue has been successfully launched on 1 May 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

Scope Indexed

WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

Abstract

DEVELOPMENT AND VALIDATION OF ULTRA VIOLET-VISIBLE SPECTROPHOTOMETRIC METHOD FOR ESTIMATION OF RIVAROXABAN IN SPIKED HUMAN PLASMA

*Souvik Rath, Chandanam Sreedhar, Harsha K Tripathy, T. Srinivasa Rao and Girindra Lekhi

ABSTRACT

To develop a simple, economic and specific validated UV method for estimation of rivaroxaban in human plasma. The diluent used is acetonitrile: water (60:40% v/v). The absorption maxima were found at 252nm. The bioanalytical procedure involves de proteination of plasma with protein precipitation extraction. The percentage of relative recovery and correlation coefficient of accuracy and precision were within acceptable limits. The method proved in simple, cost effective and sensitive for estimation of rivaroxaban in spiked human plasma.

Keywords: Human Plasma, Method Development, Protein Precipitation, Rivaroxaban, Validation.

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