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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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May Issue has been successfully launched on 1 May 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

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Abstract

DEVELOPMENT AND VALIDATION OF UV SPECTROSCOPIC METHOD FOR DETERMINATION OF METADOXINE IN BULK AND SOLID DOSAGE FORM

Rupali A. Sonawane*, Mansi A. Dhankani, Amitkumar R. Dhankani and Dr. Sunil P. Pawar

ABSTRACT

The main objective was to Develop and Validate the UV-Spectroscopy method for the estimation of Metadoxine in bulk and pharmaceutical formulations as per ICH guidelines. It showed absorption maxima at 273 nm in Methanol. The method was Linear in the range between 05-25 μg mL-1. Accuracy was found between 97.68- 98.22%. Precision for Intra-day and Inter-day was found to be within the limits. The method was Simple, Precise, Accurate and Rapid for analysis of Metadoxine in Bulk and Tablet dosage form. Hence proposed developed method can be useful for routine and quality control analysis of Metadoxine in bulk and pharmaceutical formulation.

Keywords: Metadoxine, Methanol, UV-Spectrophotometric, Melting Point.

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