Abstract

A REVIEW ON FORMULATION STRATEGIES FOR TARGETING ANTICANCER HERBAL DRUGS

Rutuja Kokane* and Dr. Dipak Raut

ABSTRACT

Cancer is a frightful ailment and represents one of the largest health-care problems for the human race and needs a proactive approach for cure. Plants are reservoirs for novel chemical entities and furnish a promising line for research on cancer. Hitherto, being effective, chemotherapy is accompanied by way of certain unbearable side effects. Nevertheless, plants and plant derived products is a revolutionizing area as these are Simple, safer, ecofriendly, low-cost, fast, and much less toxic as in contrast with conventional therapy methods. The natural drug is molded in Nano-carriers to improve developing interest in a pharmaceutical technology for a number fields in type to enlarge therapeutic worth. Nowadays, a promising interest has been developed in nanotechnology the use of herbal drugs as core material to provoke its activity on the target site. These enhancements consist of liposomes, lipid nanoparticles (LNPs), and different nanoparticles with or without macromolecular conjugates. The basis for this targeting behavior has been proven to be each passive and active targeting. The fundamental objective of this assessment used to be an overview of the distinctive formulation strategies for anticancer drugs and of the liposome-based drug delivery systems in targeted anticancer chemotherapy.

Keywords: Cancer, Formulation, Herbal drugs, Active and passive targeting, Nanoparticles.