Abstract

WOUND HEALING ACTIVITY OF PLANTS EXTRACT & THEIR POLY HERBAL FORMULATION

Gaurav Dubey*, Ravindra Pal Singh, Himmat Singh Chawra and Anurag Mishra

ABSTRACT

A wound is break in the skin (the outer layer of the skin is called the epidermis). Wound are usually caused by cuts or scalps, symptoms at wound or injury include swelling, stiffness, tenderness, discoloration skin tightness, scabbing, itching and scar formation, two types of tissue injury. The process by which tissue repair takes places is called as wound healing and is comprised of a continuous sequence of inflammation and repair, in which epithelial, endothelial, inflammatory cells, platelets and fibroblasts briefly come together outside their normal domains and interact to restore resemblances of their used discipline and having done so as to resume their normal function. The present study aims to investigate the possible wound healing effect of hydro alcoholic extracts of aerial parts of Ocimum basilicum Linn and bark of Ficus benghalensis Linn and their polyherbal formulation by topical and oral route. Wound healing studies mainly aim to detect various means and factor influencing process, so that they could be either used or avoid in clinical practice to favorably alter the healing process.

Keywords: wound, inflammation, Ocimum basilicum, Ficus benghalensis, platelets, hydro alcoholic.