Abstract

A REVIEW ON HYDROGELS: RECENT DEVELOPMENTS IN PHARMACEUTICAL FORMULATION

Monika D. Khichade*, Dr. Sameer Shafi, Mohini A. Gurav, Priyanka S. Nilangekar, Aishwarya S. Gandhale and Vishal B. Phulsundar

ABSTRACT

A hydrogel could be a water-insoluble three-dimensional polymer network that has the flexibility to soak up body fluids during a biological setting. Such a compound network is created through chemical crosslinking mechanisms like as optical polymerization, catalyst reactions and physical crosslinking such as temperature and pH dependent processes and ionic crosslinking. Physical hydrogels area unit fashioned through weak valence force and chemical hydrogels are formed by covalent forces. Varied polymers of natural and artificial origin area unit wont to create hydrogels. Swelling, mechanical properties and biological properties area unit among the foremost necessary properties of hydrogels, every of which might have an effect on the structure and morphology of the gel. thanks to its structure almost like to the animate thing matrix (ECM) and its ability to soak up water, element is employed in varied medical applications such as tissue engineering, contact lenses, wound dressings, and unharness of therapeutic agents. Hydrogels, kinds of hydrogels, their properties and applications in medication are discussed.

Keywords: Hydrogel, Antimicrobial, Crosslinking agent, Matrix.