Abstract

INVITRO EVALUATION OF ANTIMICROBIAL ACTIVITY OF YASHADA BHASMA PREPARED AS PER RASA CHANDAMSHU

Dr. Janani J.*, Dr. S. A. Doddamani and Dr. Surekha S. Medikeri

ABSTRACT

In the present era, Ayurvedic Rasaushadhies are emerging as front liners of medical practice due to their ultimate therapeutic properties on a plethora of acute and chronic disorders. Microbial infection is an acute condition that needs quick treatment in the form of different antimicrobial agents. Due to the increasing irrelevant use of antibiotics and enhanced susceptibility of microorganisms to antimicrobial agents, there are rising instances of drug resistance cases in most developing countries. Hence there is a compelling need to develop a new antimicrobial agent which is based on a targeted drug delivery system. As per Rasatarangini one of the therapeutic uses of Yashada Bhasma (Incinerated Zinc Preparation) is on Vrana and Vranasrava. Containing nanoparticles with less or no side effects along with immunomodulatory benefits, it is being used in various infectious diseases such as Dushta Vrana since ancient times but it requires to be proven and validated on the modern ground as an efficient and effective antimicrobial agent by repeated antimicrobial studies. In modern science, Zinc based preparations are commonly used in pharmaceutical products to prevent or treat topical or systemic diseases owing to their antimicrobial properties. Hence the present study deals with the Invitro Antimicrobial evaluation of Yashada bhasma prepared as per Rasa chandamshu, studied against certain Gram +ve, Gram –ve bacteria, and fungal organisms by assessment of the minimum inhibitory concentration of Yashada bhasma using Micro titre plate method. Results showed excellent antimicrobial activity in the lowest concentration of Yashada bhasma.

Keywords: Antimicrobial, Yashada, Zinc, Bacteria, Fungi.