Abstract

A REVIEW ON GOLD NANOPARTICLE USED IN CANCER TREATMENT

Akshith K.*, Hemalatha K. P. and Ayesha Kubbra

ABSTRACT

Gold nanoparticles are widely used in many fields as preferred materials used for Biosensors, different immune systems, experimental clinical sciences, genomics, laser therapy of tumors and cancer cells, drug delivery, antigens and DNA, scanning, imaging, biomolecular ultrasensitive detection, hyperthermal treatment of cancer cells, control of cancer cells and cancer tissues, cell and protein labelling for their unique optical, geometrical and physical properties, such as surface plasmon oscillations Recently, many advancements were made in biomedical applications with better biocompatibility in disease diagnosis and therapeutics. Au-NPs could be prepared and conjugated with many functionalizing agents, such as polymers, surfactants, ligands, dendrimers, drugs, DNA, RNA, proteins, peptides, and oligonucleotides. This review addressed the use of gold nanoparticles and the surface functionalization with a wide range of molecules, expanding and improving gold nanoparticles in targeting drugs for photothermal therapy with reduced cytotoxic effects in various cancers, gene therapy, and many other diseases. Overall, Au-NPs would be a promising vehicle for drug delivery and therapies.

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