Abstract

MAJOR STUDIES ON THE PHARMACOVIGILANCE SYSTEMS IN THE RECENT YEARS: AN UPDATED SYSTEMATIC REVIEW

Amitder Nath Chatterjee* and Barsha Giri

ABSTRACT

Pharmacovigilance is primarily a study of the safety of medications that are marketed for therapeutic use in practical settings for broader communities. Adverse Drug Reactions are defined as an unpleasant sort of reaction caused by an intervention associated with the use of a medical product at the recommended dosage level. It is classified into six categories, ranging from A to F. India has one of the greatest pharmaceutical industries in the world, valued at over $18 billion, and exports nearly 40 percent of all generic medications worldwide. To ensure better health and safety in such a densely populated country, a proper pharmacovigilance and drug safety monitoring programme is critical. Surveillance for adverse drug responses developed quite late in India, as there was no such notion for medicine surveillance in India previously. India formally joined the WHO ADR monitoring programme in Uppsala, Sweden, in 1997. Medicinal goods undergo utilisation to produce a beneficiary effect. However, in some situations, these products have been linked to a variety of Adverse Events (AEs), which typically result in disease, injury, and, in some cases, death. Normally, expected AEs must be limited to a particular amount that can be accommodated within the benefit-risk balance calculation. In the current review, a collaborative study based on pharmacovigilance system carried out in the recent years has been show so that it could be further utilized by others for future studies.

Keywords: Pharmacovigilance, Adverse drug reactions, Thalidomide, Pharmacoepidemiology.