Abstract

FORMULATION AND EVALUATION OF POLYHERBAL MOUTHWASHES

Tejashwini H.*, Harsimran Kaur Kohli, R. Vijay and Dhayalan M.

ABSTRACT

The purpose of this research is to formulate and evaluate herbal mouthwash in order to treat and prevent oral microbial burden by using the extract of curcumin and Xylitol. The curcumin added in the preparation to serves as anti-inflammatory and antioxidant. Xylitol formulation helps in preventing harmful bacterial development and helps in maintaining oral hygiene. The mouthwash prepared using curcumin and xylitol was subjected to various evaluation parameters like PH, appearance, odor. Here the herbal mouthwashes containing five formulations as f1, f2, f3, f4 and f5. The PH (6.76) standard preparation was compared with four preparations (f1,f2,f3,f4).The PH of f1 preparation is 5.78,f2 was 6.0 ,f3 was 6.43,f4 was 6.66.As compared to standard preparation f4(6.66) shows the nearer value of PH. The Appearance of the prepared mouthwash was found to be blue colour clear liquid. The odor of prepared mouthwash was found to be odor of fresh mint with Nutmeg oil, Eucalyptol oil and fennel oil. The HPLC analysis of Sodium methyl paraben was found to be (0.142,0.141,0142,0.141,0.141%w/w). and sodium Propyl Paraben was found to be (0.050,0.050,0.051,0.051%w/w).The Evaluation parameter confirmed that the formulated mouthwash served the purpose.

Keywords: Sodium Propyl Paraben, Herbal mouthwash, Curcumin and Xylitol.