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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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May Issue has been successfully launched on 1 May 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

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Abstract

COMPARISON OF ANTIFUNGAL ACTIVITY OF FORMULATED FLUCONAZOLE GEL USING NATURAL POLYMER WITH MARKETED FORMULATION

Shivani Shashikant Hippargi*, Utkarsha Shivsharan and Vrushali Ravikant Patil

ABSTRACT

The purpose of this study is to compare the antifungal activity of formulated Fluconazole gel using natural polymer with marketed formulation. Different formulations were formulated using different concentrations of polymer ratios of Guar Gum & Agar. The agar well diffusion technique was utilized to test the antifungal activity of the formulations against Candida albicans & Aspergillus Niger. The inhibition zone related to each formulation was measured in millimeters after 48, and 72 hours of incubation at 37°C. The highest zone was found in F4 formulation while the lowest was seen in F9 & F8 for C. Albicans & A. Niger respectively. F4 formulation showed an excellent zone of inhibition with 10mm & 18mm diameter. Conclusion, F4 formulation showed more zone of inhibition compared to marketed formulation.

Keywords: Fluconazole, Candida Albicans, Aspergillus Niger, Antifungal Activity.

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