Abstract

DIURETICS: A PHARMACOLOGICAL APPROACH

*Haripriya S., Shalini P., Femilarani J., Sharmila K. and Elavarasi K.

ABSTRACT

Diuretics is promoting the execration of water from the body. Urinary system is composed of two kidneys, the functionally filtering apparatus, which connect through structures called ureters to a urinary bladder, serve as a reservoir for urine. Urine formation occurs in three stages i) glomerular filtration, ii) tubular reabsorption, iii) tubular secretion. Therapeutic uses of diuretics are reducing high Blood Pressure. Cardiac disorders lead to vasoconstriction, and a decreased glomerular filtration rate. When decreased glomerular filtration rate is associated with increased salt and water retention. Diuretics used to reduce the retention of salt so cardiac patients advised to take these pills. The classification of diuretics are Loop diuretics, Thiazides diuretics, Carbonic anhydrase inhibitors, Potassium sparing diuretic, Osmotic diuretics. Furosemide, Hydrochloro-thiazide, Acetazolamide, Spironolactone, Mannitol etc., these are the drugs that are familiar to treat diuretics. In this article we want to share a drugswhich are used as diuretics.

Keywords: Urinary bladder, glomerular filtration, tubular reabsorption, tubular secretion, Carbonic anhydrase inhibitors, Potassium sparing diuretic, Osmotic diuretics.