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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

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WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS: MAY ISSUE PUBLISHED

May Issue has been successfully launched on 1 May 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

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WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

Abstract

ANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF NICKEL CONTENT IN SORBITOL BY INDUCTIVELY COUPLED PLASMA MASS SPECTROMETRY (ICP-MS)

Rattaiah Gupta T.* and Dr. G. Devala Rao

ABSTRACT

A Method for determination of Nickel content in Sorbitol by ICP-MS and method was validated and applied, for routine analysis in ICP-MS technique. Inductively coupled plasma mass spectrometry (ICP-MS) excellent tool for characterization of the elementary composition of many samples. In this study Nickel metal as described toxic metal defined in USP(233) linearity, Method precision, Accuracy, Robustness and ruggedness parameters have been taken into account and evaluated for the method validation. The results obtained for the recovery of Nickel metals between 92.0 % and 101.4 % were found. The detection limits of all elements studied showed the suitability of the procedure for routine analyses. Summarizing it can be concluded that the described analytical procedures to measure the mass fractions Nickel elements in Sorbitol samples.

Keywords: ICP-MS, Element analysis, method validation.

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