Abstract

FORMULATION AND EVALUATION OF FAST DISSOLVING FILMS OF ANTI HYPERTENSIVE DRUG

D. Annapoorna* and M. V. Jhansi Priya

ABSTRACT

Drugs absorbed from the mouth, throat, and oesophagus are transported into the stomach by saliva. As compared to traditional dose forms like tablets and capsules, the bioavailability of medications is much higher when administered in this manner. This condition is expected to impact between 35 and 50 percent of the population. The goal is to make the medication molecule more effective and safe. Angiotensin-converting enzyme (ACE), the enzyme that converts angiotensin I (ATI) to angiotensin II (ANI), is a powerful, competitive inhibitor of Captopril (ATII). The renin-angiotensin-aldosterone system relies on ATII to regulate blood pressure (RAAS). In the treatment of hypertension, Captopril may be used Bioavailability of captopril, a drug that is 70-75 percent soluble in a variety of common organic solvents, is estimated

Keywords: Captopril, Fast Dissolving films, Bioavailability.