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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

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Abstract

EVALUATION OF HAEMATOLOGICAL PARAMETERS OF ETHANOL LEAF EXTRACT OF GONGRENEMA LATIFOLIUM IN ADULT DIABETIC-INDUCED ABLNIO RATS

Joseph Chikezie Enye, P.C. Unekwe, IFeoma N. Nweke and Emmanuel Ifeanyi Obeagu*

ABSTRACT

Gongrenema latifolium is used by traditional healers in different localities for the treatment of various ailments including Diabetes mellitus without any scientific proof or validation. This study is aimed at evaluating haematological parameters of ethanol leaf extracts of Gongrenema latifolium in adult diabetic-induced albino rats. The extract was done using cold maceration method. The acute toxicity (LD50) of ethanol extracts was determined by the method of Lorke and the phytochemical analysis were determined using the method of Trease and Evans. Statistical analysis was carried out using ANOVA. However, the extracts have negative effect on the haematologica indices leading to reduction in their values. The extract reduced the values of the haematological indices in dose-dependent manner.

Keywords: Gongrenema latifolium, Haematological parameters, Albino rats, diabetes.

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