Abstract

A REVIEW ON ANALYTICAL METHODS FOR SIMULATANEOUS ESTIMATION OF RESVERATROL AND QUERCETIN

Tejaswini G. Malge*, Madhuri D. Game, Akash S. Malthankar, Vaishnavi S. Kalamb

ABSTRACT

The development and validation of analytical methods is important for any drug development program. In the discovery, development, and manufacture of pharmaceuticals, analytical method development and validation play an important role. Every year, a large number of drugs are introduced into the market, necessitating the development of newer analysis procedures for such drugs. Validation of the novel analytical method is required after development. Analytical technique development is used to determine a drug's identification, purity, physical characteristics, and potency, as well as its bioavailability and stability. Analytical method development involves the evaluation and selection of the most precise assay procedures to determine drug`s composition. Analytical method development entails analyzing and selecting the most exact test procedures for determining a drug's composition. Analytical chemistry, which includes procedures for identifying, separating, and quantifying the chemical components of pharmaceutical substances, is used to develop methods. Validation of the new analytical process is needed after development. The process of proving that an analytical method is suitable for use is known as method development. Validation parameters such as accuracy, precision, linearity, limit of detection, limit of quantification, specificity, range, and robustness are used in compound testing methods. Validation should be carried out in accordance with guidelines such as the ICH guidelines.

Keywords: Simultaneous, method, Spectroscopy, HPLC, development, validation, quercetin, resveratrol.