Abstract

FORMULATION AND EVALUATION OF ANTIMICROBIAL ACTIVITIES OF HERBAL GEL OF ALCOHOLIC EXTRACT OF ALOE BARBADENSIS MILLER

M. Sakthivel*, B. Prathap, R. Mahendiran, M. Parthiban, M. Naveetha and M. Arivananthan

ABSTRACT

The antimicrobial activity of ethanolic extract of dried leaves of aloe vera is formulated and evaluated. The preliminary invitro antimicrobial activity of the extract at various concentration and those of their gel were determined against some microorganisms using the agar cup plate method. The growth inhibition zones of the extracts on the micro-organisms were noted. The minimum inhibitory concentration (MIC) was also determined by agar dilution method. The physical properties of the gel formulated with the extract were evaluated using standard procedures. The fungal strain Candida albicans had the lowest MIC value (2.0mg/ml) for the aloe Vera gel extract.

Keywords: Aloe-vera, Herbal gel, Antimicrobial activity, Candida albicans.