Abstract

EFFECT OF ELYTRARIA ACAULIS ACETONE EXTRACT ON FERTILITY IN MALE ALBINO RATS

Venkat Raji Reddy.G*, Vijay Kumar.R, Sathyanarayana.J and Krishna Reddy.M

ABSTRACT

Surgeries like vasectomy, tubectomy and medication (contraception) for the population control are not fully restraining the population growth. Medicine available to control birth rate carrying side effects. The attempt of exploring the importance of Ayurveda the present work was carried out. The acetone extract of the plant Elytraria acualis was prepared by maceration technique. Extract effects the fertility by reducing the sperm count and motility in the albino rats. The male albino rats were divided into three groups of eight animals in each. The first group was considered as control and Group II, III were treated with dose 200mg/kg and 300mg/kg extracts respectively. The treatment of the extract was carried out by gastric gavage for 21 days through oral. The rats were sacrificed to study sperm count and motility. The blood samples were centrifuged to separate serum. The serum samples used for the serological parameters. The reduced levels of vital reproductive organs weights and sperm count, motility were observed in the treated rats compare to control. The cholesterol, triglycerides increased and glucose levels were decreased in the serum of treated rats. The glycogen and protein levels of testes and liver were decreased in the treated groups than to the control group. The histological sections of testes in treated groups were observed that loss of interstitium and degenerated germinal cells were also observed in the treated groups. The effect of the extract was more in group –III compare to group- II.

Keywords: Elytraria acaulis, SGOT, SGPT, Triglycerides.