Abstract

CHEMICAL CONSTITUENTS FROM THE AERIAL PARTS OF TRICHOSANTHES DIOICA ROXB.

Chetna Kharbanda, Mohammed Ali*, Mohammad Sarwar Alam, Hinna Hamid, Shahnaz Sultana and Showkat Rassol Mir

ABSTRACT

Trichosanthes dioica Roxb. (family Cucurbitaceae), is an annual or perennial herbaceous vine, used to treat acidity with constipation, diarrhoea, anal fistula, leprosy, inflammations, enlarged liver and spleen, alcoholism, jaundice, edema, alopecia and wounds. Our study was planned to isolate chemical constituents from a methanolic extract of the aerial parts of this plant and to characterize their structures on the basis spectral data analysis. Phytochemical investigation of the aerial parts of T. dioica led to isolate a known glycerol trioleate characterized as 1,2,3-trilinoleoylglycerol (trilinolein, 1), a fatty acid ester identified as n-docosanyl octadec-9(Z)-enoate (n-docosanyl oleate, 2), a new aliphatic alcoholic xyloside formulated as 5α-hydroxy-n- docosanolyl-O-β-D-xylopyranoside (3), a familiar phenolic constituent namely 1,3,5-benzenetriol (phloroglucinol, 4), a known monosaccharide characterized as -L-xylose (5) and an unknown ketolanostene diglucoside and its structure was established as lanost-5-en-3β-olyl-3-O-α-D-glucopyranosyl-(3′→1′′)-O-α-D-glucopyranoside (6). All these phytoconstituents have been isolated for the first time from the aerial parts of this plant.

Keywords: Trichosanthes dioica, aerial parts, phytoconstituents, isolation, spectra analysis.