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STUDY OF ANTI-EPILEPTIC EFFECT OF COMBINATION DRUG GREEN TEA EXTRACT AND CURCUMIN IN MICE
Muralidharan P.*, Sabbathyan Balla, T. Sheela and Jiji K. N.
ABSTRACT Aim: To evaluate the anti-epileptic activity of combination drug of green tea and curcumin Extract. Method: The anti-epileptic activity of combination drug of green tea and curcumin extract is studied by Maximal electroshock seizures (MES) Convulsions and Pentylenetetrazole (PTZ) induced convulsions methods using Swiss Albino Mice (n=6) divided into five groups. Results: The levels of GABA and glutamate in the PTZ induced seizures significantly increase (p value Keywords: Pentylenetetrazole (PTZ), Maximal electroshock seizures (MES), GABA, Glutamate. [Download Article] [Download Certifiate] |
