Abstract

THE CONCEPT OF 3D PRINTING FOR ORAL DOSAGE FORM

Vishwas Bhaurao Talekar*, Akshay Uttam Gaikwad, Sahil Manoj Tharewal, Vikki Sominath Jadhav, Manoj Shere and Gajanan S. Sanap

ABSTRACT

A layer-by-layer process to produce drug products has gaining lot of Attention in recent years especially after its first FDA approved because of several Advantages offered as an effort for improved pharmacotherapy. This technology Is indeed an old and widely used in other industries. However due to various Regulations and complex application, it is yet to flourish Author in the Pharmaceutical industry. Despite this fact, various dosage forms have been Prepared and reported in the literature using this technology. The food and Drug Administration (FDA) recently approved the first 3D printed drug, anti-epilepsy drug Called spritam, made with Aprecia Pharmaceuticals proprietary 3D printing Technology, ZIPDOSE. This review article highlights the numerous formulation strategies Available at the disposal of the formulation scientist to manufacture solid oral Dosage form with desired drug release profile. Also, it provides basic Understanding of the various 3D printing manufacturing techniques available to Manufacture solid oral dosage forms.[1] Overall, this review on 3d printing technology has described the advancement in manufacturing and futuristic potential for therapeutic approach to bring in vast array of useful application and benefits to human.

Keywords: 3D printing, Pharmacotherapy, Anti-epilepsy, Spritam, Zipdose, Oral dosage form, Therapeutic approaches.