A REVIEW OF ANALYTICAL METHODS FOR DETERINATION AND ESTIMATION OF VILDAGLIPTIN
B. Renuka* and T. Ram Mohan Reddy*
ABSTRACT
The review represents different analytical techniques like ultra-violet spectroscopy, high performance liquid chromatography, reversed phase-high performance liquid chromatography, liquid chromatography used for the determination of Vildagliptin in drug substance, related compounds, tablet dosage form, combination with other drugs, biological fluids. Analytical method development and validation plays key role in drug development process starting from formulation to final product. during development process. Active pharmaceutical ingredient contains many organic, inorganic impurities
which lead several toxic effects. This impurities was separated by using different analytical techniques. Analytical technique is applied to produce out comes for the quality of medicine. Purpose of this literature review is to provide a systematic survey of the analytical methods used for estimation of Vildagliptin until today.
Keywords: Vildagliptin, Anti-Hyperglycemia Agent, RP - HPLC, HPTLC, UPLC, LC-MS, UV - Spectrophotometry.
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