Abstract

REVIEW ON NANOTECHNOLOGY: SOLID-LIPID NANOPARTICLES

Sonal Satpute*, Vaishali Mahadik, Dipti Patil and Monika Chavare

ABSTRACT

Solid lipid nanopaticles were developed in the early 1990s as an alternative to standard colloidal carriers such as liposomes, polymeric nanoparticles, and emulsions because they offer benefits such as controlled drug release and targeted drug delivery with greater stability. Olid lipid nanoparticles (SLN) are at the forefront of nanotechnology's rapid development, with numerous potential applications in medication delivery and research. Lipid nanoparticles have the potential to generate novel therapies due to their unique size-dependent characteristics. The ability to insert pharmaceuticals into nanocarriers provides a new drug delivery paradigm that could be used for medication targeting. As a result, solid lipid nanoparticles have piqued researchers' interest as a means of achieving the goal of regulated and site-specific medication delivery. This article presents a broad treatment of solid lipid nanoparticles discussing their method of preparation, advantages, limitations and their route of administration.

Keywords: Solid-lipid nanoparticles, Colloidal drug carriers, Homogenization, Biodistribution targeting.