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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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Updated Version

WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

Call for Paper

WJPPS Invited to submit your valuable manuscripts for Coming Issue.

Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

New Impact Factor

WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS: MAY ISSUE PUBLISHED

May Issue has been successfully launched on 1 May 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

Scope Indexed

WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

Abstract

SOLUBILITY ENHANCEMENT TECHNIQUES-A LITERATURE REVIEW

Vaibhav Bhor*, Avinash Tapkire, Prof. Dr. R. S. Bacchav and Smita Aher

ABSTRACT

Orally administered drugs are completely absorbed only when they have a fair solubility in gastric medium and such drug show high bioavailability. Recently, more than 40% of new drug developed in the pharmaceutical industry are practically insoluble in water. These drugs' inability to dissolve in water, associated with slow absorption, results in insufficient and variable bioavailability. Hence various techniques are used for the improvement of the solubility of poorly water-soluble drugs include micronization, Nanonization, Surfactant, pH adjustment, Co-solvency, particle size reduction, Polymeric Alteration, Solvent Deposition/Evaporation, Co-crystallization, hydrotropy.

Keywords: Techniques of solubility enhancement, Nanonization, Polymeric Alteration.

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