Abstract

AN OVERVIEW: NATURAL ANTIVIRAL AGENT AND CURRENT CHALLENGES IN ANTIVIRAL TREATMENT

Monika Chavare*, Sonal Satpute, Dipti Patil and Vaishali Mahadik

ABSTRACT

Medicinal herbs have been widely utilized to treat viral diseases, which are still the largest cause of death in humans globally, and are caused by pathogenic virus infection, which has a high morbidity and mortality rate. Plant-based medications are in high demand since they are regarded to be safer, non-toxic, and less dangerous than synthetic treatments. Several hundred plant and herb species have been identified as having potential as novel antiviral agents and a wide variety of active phytochemicals, such as flavonoids, terpenoids, lignans, sulphides, polypheolics, coumarins, saponins, furyl compound, alkaloids, polylines, thiophenes, protein, and peptides. Plaque reduction tests were used to assess antiviral activity, and the method of antiviral action was investigated by administering the medicines to uninfected cells, the virus prior to infection, or herpes virus-infected cells. For their various therapeutic roles, a large variety of biologically active compounds have been found. In this article we major focus on viral infection, Strategies for antiviral screening. Common stages in the viral life cycle, Current challenges in antiviral treatment, Natural products as a source for broad-spectrum antiviral drugs.

Keywords: Antiviral agent, Viral life cycle, Current challenges in treatment, Natural product.