Abstract

TYPHOID

Shingare S.S.S.*, Prof. Deshmukh S. and Prof. Bawage S.B.

ABSTRACT

Typhoid fever is widespread in Asia, especially in developing countries Asia like India, caused by the gram-negative bacterium Salmonella enterica serval Typhi.It is an infectious disease of the mouth caused by eating contaminated food water. The incubation period is 7 to 14 days. Symptoms include high fever, rash, weakness, bloating, abdominal pain, and loss of appetite. Antibiotic resistance is key problem to manage successfully. First-line drugs are less commonly used to treat typhoid and are resistant it comes from fluoroquinolones. The only remaining drug choice is ceftriaxone and azithromycin. At the antagonistic action of typhoid fever is primarily on personal and home hygiene. Offering of clean water and safe sanitation should be used to eliminate S. Typhi. Good observation, better diagnosis, more sensible use of antibiotics and effective vaccination will be essential to reduce the burden of diseases caused by S. Typhi.

Keywords: Typhoid, Salmonella Typhi, Drug resistance, Food-borne illness, Proteomic approach.