Abstract

A SYSTEMATIC REVIEW OF THE MEDICINAL USES OF AZANZA GARCKEANA

Yunusa Abdulmajeed* and Etuk C. Claire

ABSTRACT

Azanza garckeana is a cash crop in Nigeria that is mainly seen and marketed in Northern Nigeria with several medicinal claims. We conducted a systematic review on the medicinal uses of the plant extract. The review was designed and conducted according to the provided guidelines of Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA). We identified a total of 22 published articles through literature search. After removing duplicates and irrelevant articles, a total of 8 articles were selected for this review. The concentrations of the plant extract used ranges from 12.5μg/ml to 100 μg/ml for in-vitro studies and 150mg/kg to 600mg/kg for in-vivo studies. Azanza garckeana exhibited a variety of biological effects including antioxidant, antimicrobial, anti-inflammatory, aphrodisiac, uterotonic, analgesic, antiarthritic, haematologic, and wound healing activities. The proposed mechanisms of action of the observed effects were due to presence of different phytochemicals found in either the fruit, bark, root or the stem.

Keywords: Azanza garckeana, Medicinal-uses, Systematic-review.