Abstract

A SPECIAL EMPHASIS ON THERAPEUTIC DRUG MONITORING (TDM): MODERN FEATURE IN PHARMACOLOGY & TOXICOLOGY

Swapnil S. Lad*, Shweta S. Kate, Mahesh G. Kamble and Abhijeet H. Patil

ABSTRACT

Therapeutic drug monitoring (TDM) is a medical exercise for dose individualization. Broadly, the time period refers to measuring precise pills at targeted periods to hold a steady concentration in affected person's bloodstream, thereby optimizing character dosage regimens. When a pharmacokinetic (PK) version is to be had for a drug, multiple concentrations can be measured within a dosing c language and PK equations may be used to estimate an individual affected person’s PK parameters. For several drug lessons, TDM is ordinary a part of scientific practice used for all patients as a part of their therapy. For other tablets, the want for TDM may be decided on a case-through-case foundation. The aim of TDM is to apply suitable concentrations of medications to optimize medical effects in patients in various clinical conditions.

Keywords: Pharmacokinetics, Therapeutic index, Drug interaction, Blood concentration.