Abstract

ANALYTICAL TECHNIQUES FOR THE DRUGS USED IN THE TREATMENT OF VASCULITIS– A REVIEW

Asha Deepti C.* and Mannava Sangeetha

ABSTRACT

Vasculitis is a blood vessel inflammation. It occurs when the immune system of the body accidentally attacks a blood vessel. It could be caused by an infection, a drug, or another illness. The arteries, veins, and capillaries can all be affected by vasculitis. The most common signs and symptoms include fever, headache, fatigue, weight loss, general aches and pain. According to the Chapel Hill Consensus Conference, the primary categories of vasculitis can be classified based on clinical and pathological data. Because aetiology and pathophysiology are rarely defined, and clinical and histological characteristics overlap, a definitive classification of systemic vasculitis is problematic. Other disorders, such as systemic lupus erythematosus and rheumatoid arthritis, might include vasculitis as a side effect. Some of the drugs used in the treatment are Prednisolone, Leflunomide, Cyclophosphamide, Methotrexate, Azathioprine. A brief review of the analytical methods developed for the estimation of these drugs is discussed in the present study.

Keywords: Vasculitis, Prednisolone, Leflunomide, Cyclophosphamide, Methotrexate, Azathioprine.