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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

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Abstract

NOVEL METHOD FOR ESTIMATION OF FLUORIDE ION IN PHARMACEUTICAL PREPARATIONS, TOOTH PASTES AND VARIOUS ENVIRONMENTAL SAMPLES

Nief Rahman Ahmed*, Rawya Nathem Rashed and Alaa Ali Hussein

ABSTRACT

A new indirect spectrophotometric method for the estimation of fluoride ion has been developed. The method is based on the formation of the fluoride complex which bleach the color of Ti(IV) with 2-hydroxy-1- (2-hydroxy-4-sulfo-1-naphthylazo)-3-naphthanic acid (HHSNNA) complex with proportional decrease of absorbance. Therefore the decrease in color intensity is proportional to the concentration of fluoride ion. Molar absorptivity is 0.38x103 l/mol.cm at wavelength 685 nm. Beer s law is obeyed in the concentration range of 0.2- 3. 6μg/ml. The method is applied successfully to determination of fluoride ion in different real water samples, different brand of toothpastes pharmaceutical preparations and various brand tea infusions.

Keywords: fluoride ion, toothpastes, pharmaceutical preparations, Environmental Samples.

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