Abstract

NANO SPONGES: A NOVEL APPROACH FOR TARGETED DRUG DELIVERY SYSTEMS

Mihir Otia, Krishna Joshi, Nirmal Joshi, Chandrakanta, Dolly Jayesh Mukhi, *Deepak Chandra Joshi

ABSTRACT

To put it another way, targeted drug delivery systems are unusual in that the pharmacologically active experts are only concerned with their site action and not the non-targeted organs, tissues or cells. Nano sponges are powerful pharmaceutical transporters that address difficulties like as harmfulness and inadequate bioavailability, such as the ability to stack hydrophilic and hydrophobic medications together. Nano sponge can stack a variety of pharmaceutical classes for targeted medication delivery. One of the most encouraging methods in the history of science is this approach of delivering drugs precisely where they are needed. Despite their diminutive size and three-dimensional structure, nanosponges have the ability to deform on the nanometer scale. Nanotechnology's most recent creative advance has resulted in the development of a targeted medicine delivery method. The usage of specialised drug delivery systems is required to effectively target a molecule to a specific place using a drug delivery system. Conventional drug delivery technologies have been greatly improved by the development of Nano sponges. Both hydrophilic and hydrophobic medicines can be carried by them. The controlled and predictable release of the medicine to the targeted site is generally provided by nano sponge technology. The medicine is released when the Nano sponge particles connect to the target spot and circulate throughout the body. Due to its porosity nature, the Nano sponge formulation can accommodate a wide range of medications. There is a lot of interest in nano sponge technology for the delivery of drugs by oral, topical and parenteral administration. Nano sponges can be utilised to halt the degradation of drugs and proteins. Nano sponges can also boost the solubility of drugs that aren't very water-soluble. A variety of therapeutic formulations and recent studies on Nano sponge were examined for their benefits, composition, preparation process, evaluation, and use in this review.

Keywords: Nano sponges, Targeted drug delivery, Controlled drug delivery, Solubility.