Abstract

THE ASSOCIATION OF OXIDIZED HIGH DENSITY LIPOPROTEIN AND OXIDIZED NON-HIGH DENSITY LIPOPROTEIN WITH THE DEVELOPMENT OF MICROALBUMINURIA IN DIABETIC NEPHROPATHY

Mohammed A. Al-Bayati,  Dina A. Jamil, Hayder A. Al-Aubaidy*

ABSTRACT

This study was undertaken to investigate the association of total lipid peroxides and oxidized HDL in the progression of microalbuminuria in diabetic nephropathy. Fifty-five patients with type 2 diabetes mellitus were recruited in this study and were divided into 2 main groups based on the presence of microalbuminuria, the first group (microalbuminuric group n=31) had a microalbuminuria between 30- 299 ug/mg. The second group (normoalbuminuric group, n=29) had an albumin level less than 30 ug/mg. The two diabetic groups were compared to the control group (n=37). The results of our study showed significant elevation in the levels of serum lipid profiles and lipid peroxidation markers in the microalbuminuric group compared to the normoalbuminuric group at P

Keywords: Serum lipids, lipid peroxidation, microalbuminuria, type 2 diabetes mellitus.